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. 2017 Dec 7;9(1):622–640. doi: 10.18632/oncotarget.23079

Table 5. The significantly down-regulated lipid metabolism-related genes in the suspension MDA-MB-468 cells.

Gene Description log2(fold_change)
PTGIS Prostaglandin I2 (Prostacyclin) Synthase –4.38964
APOC1 Apolipoprotein C1 –4.26849
APOL1 Apolipoprotein L1 –4.14778
PCSK9 Proprotein Convertase Subtilisin/Kexin Type 9 –3.98917
A4GALT Alpha 1,4-Galactosyltransferase –3.13062
FAXDC2 Fatty Acid Hydroxylase Domain Containing 2 –2.94314
PNPLA3 Patatin Like Phospholipase Domain Containing 3 –2.94113
SCD Stearoyl-CoA Desaturase –2.85593
FGF2 Fibroblast Growth Factor 2 –2.84993
DHCR7 7-Dehydrocholesterol Reductase –2.66095
ETNK2 Ethanolamine Kinase 2 –2.61412
ELOVL4 ELOVL Fatty Acid Elongase 4 –2.47722
FASN Fatty Acid Synthase –2.44083
FADS1 Fatty Acid Desaturase 1 –2.19383
INSIG1 Insulin Induced Gene 1 –2.19298
EBP Emopamil Binding Protein (Sterol Isomerase) –2.18836
MVD Mevalonate Diphosphate Decarboxylase –2.13654
ELOVL3 ELOVL Fatty Acid Elongase 3 –2.03057
MVK Mevalonate Kinase –2.02055
LSS Lanosterol Synthase (2,3-Oxidosqualene-Lanosterol Cyclase) –1.91218
IDI1 Isopentenyl-Diphosphate Delta Isomerase 1 –1.88897
FDPS Farnesyl Diphosphate Synthase –1.84979
LDLR Low Density Lipoprotein Receptor –1.82226
C14ORF1 Chromosome 14 Open Reading Frame 1 –1.73982
HSD17B11 Hydroxysteroid 17-Beta Dehydrogenase 11 –1.72799
CYP27A1 Cytochrome P450 Family 27 Subfamily A Member 1 –1.71884
FDXR Ferredoxin Reductase –1.70033
FDFT1 Farnesyl-Diphosphate Farnesyltransferase 1 –1.68175
GBGT1 Globoside Alpha-1,3-N-Acetylgalactosaminyltransferase 1 –1.65937
ST6GALNAC6 ST6 N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 6 –1.63569
SOAT1 Sterol O-Acyltransferase 1 –1.62789
GGT5 Gamma-Glutamyltransferase 5 –1.6126
ISPD Isoprenoid Synthase Domain Containing –1.61245
TECR Trans-2,3-Enoyl-CoA Reductase –1.60378
ISYNA1 Inositol-3-Phosphate Synthase 1 –1.57524
DHCR24 24-Dehydrocholesterol Reductase –1.56679
LPCAT4 Lysophosphatidylcholine Acyltransferase 4 –1.5494
MGST2 Microsomal Glutathione S-Transferase 2 –1.5233
PECR Peroxisomal Trans-2-Enoyl-CoA Reductase –1.4498
ACLY ATP Citrate Lyase –1.43626
SCD5 Stearoyl-CoA Desaturase 5 –1.4233
NSDHL NAD(P) Dependent Steroid Dehydrogenase-Like –1.42082
CERCAM Cerebral Endothelial Cell Adhesion Molecule –1.41546
CYP51A1 Cytochrome P450 Family 51 Subfamily A Member 1 –1.3948
ELOVL7 ELOVL Fatty Acid Elongase 7 –1.38885
SQLE Squalene Epoxidase –1.37995
ACSS2 Acyl-CoA Synthetase Short-Chain Family Member 2 –1.35018
MIF Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) –1.33722
CYP7B1 Cytochrome P450 Family 7 Subfamily B Member 1 –1.23914
ALOX5 Arachidonate 5-Lipoxygenase –1.2341
PLAUR Plasminogen Activator, Urokinase Receptor –1.23365
TPI1 Triosephosphate Isomerase 1 –1.20651
PIGU Phosphatidylinositol Glycan Anchor Biosynthesis Class U –1.2031
CYB5R3 Cytochrome B5 Reductase 3 –1.19764
CHPT1 Choline Phosphotransferase 1 –1.19349
SC5DL Sterol-C5-Desaturase –1.19039
ACSL3 Acyl-CoA Synthetase Long-Chain Family Member 3 –1.18695
PIGS Phosphatidylinositol Glycan Anchor Biosynthesis Class S –1.11575
PCYT2 Phosphate Cytidylyltransferase 2, Ethanolamine –1.08604
SCARB1 Scavenger Receptor Class B Member 1 –1.0724
HMGCR 3-Hydroxy-3-Methylglutaryl-CoA Reductase –1.04385
HMGCS1 3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 –1.03708
MBOAT2 Membrane Bound O-Acyltransferase Domain Containing 2 –1.02974
HSD3B7 Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- And Steroid Delta-Isomerase 7 –1.02875
ELOVL1 ELOVL Fatty Acid Elongase 1 –1.02678
CAT Catalase –1.01705
SIGMAR1 Sigma Non-Opioid Intracellular Receptor 1 –1.00092