Table 3. Different inheritance model analyses of rs11646213 in CDH13 between NSCLC and control groups (After adjusted for gender and age).
Models | Genotypes | Control (n, %) | NSCLC (n, %) | OR (95% CI) | P-value* | AIC | BIC |
---|---|---|---|---|---|---|---|
Codominant | A/A | 316 (71.2%) | 292 (64.3%) | 1.00 | 0.011 | 1207.6 | 1490.8 |
A/T | 118 (26.6%) | 138 (30.4%) | 1.16 (0.84–1.61) | ||||
T/T | 10 (2.2%) | 24 (5.3%) | 3.43 (1.47–8.00) | ||||
Dominant | A/A | 316 (71.2%) | 292 (64.3%) | 1.00 | 0.110 | 1212.0 | 1490.4 |
A/T-T/T | 128 (28.8%) | 162 (35.7%) | 1.30 (0.95–1.77) | ||||
Recessive | A/A-A/T | 434 (97.8%) | 430 (94.7%) | 1.00 | 0.004 | 1206.4 | 1484.8 |
T/T | 10 (2.2%) | 24 (5.3%) | 3.26 (1.41–7.56) | ||||
Overdominant | A/A-T/T | 326 (73.4%) | 316 (69.6%) | 1.00 | 0.640 | 1214.4 | 1492.8 |
A/T | 118 (26.6%) | 138 (30.4%) | 1.08 (0.78–1.49) | ||||
Log-additive | --- | --- | --- | 1.38 (1.05–1.81) | 0.019 | 1209.1 | 1487.5 |
*Statistical significant threshold was set at P < 0.007 (0.05/7) determined by Bonferroni correction.