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. 2017 Dec 8;9(2):2058–2075. doi: 10.18632/oncotarget.23156

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Copyright: © 2018 Ikram et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) Flow cytometric analysis of EL4 cells for the expression of the lymphoma stem cell markers c-Kit and Sca-1. Percentages of the cell population expressing c-Kit⁺/Sca-1⁺ in EL4 cells cultured under 2D and 3D conditions are presented. Data represent the means ± SD of three independent experiments. ^***P < 0.001 versus the control. (B) Confocal microscopic analysis of EL4 cells for the expression of c-Kit and Sca-1. Immunofluorescence images show the distribution features of lymphoma stem cells in the spheroids. Scale bar, 40 μm.