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. 2017 Dec 19;9(2):2384–2394. doi: 10.18632/oncotarget.23415

Figure 1. ABC294640 inhibits human cervical carcinoma cell growth.

Figure 1

mRNA and protein expressions of SphK2 in the established human cervical carcinoma cells (C33A/HeLa), two primary human cervical carcinoma cells (“P1” and “P2”), or primary human cervical epithelial cells (“E1” and “E2”) were shown (A and B). The above cells were either left untreated (“C”) or treated with ABC294640 at designated concentrations (0.1-10 μmol/L), cells were further cultured for applied time; cell growth was tested by the listed assays (C-E, G and H); cell cycle progression was also tested (F, for C33A cells). Data were shown as mean (n=5) ± standard deviation (SD). *p<0.05 vs. “C” cells. Experiments in this figure were repeated three times, and similar results were obtained.