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. Author manuscript; available in PMC: 2018 Jan 30.
Published in final edited form as: Virology. 2013 May 29;443(1):11–19. doi: 10.1016/j.virol.2013.04.033

Figure 1.

Figure 1

HPV genes needed for late promoter activation. a. The early region of the HPV16 genome, with the locations of the early and late promoters and the E1 splice donor. The region contained in the late promoter luciferase reporter is indicated. b. HFK cells, HFKs containing the episomal HPV16 genome, or HFKs expressing E6 or E7 from retroviral vectors were transfected with the late promoter reporter and incubated for 24 hours in monolayer or MC culture. Luciferase values were normalized to Renilla luciferase internal controls and to the monolayer value for each cell type. Values are the mean of 5-12 experiments. Bars represent ± one standard error of the mean.