Table 1. Echocardiographic and hemodynamic analysis of mice one week after sham or LAD ligation.
| Sham | MI | |||
|---|---|---|---|---|
| Vehicle (n = 5) | RFP (n = 5) | Vehicle (n = 5) | RFP (n = 5) | |
| LVAWd (mm) | 0.72 ± 0.03 | 0.74 ± 0.04 | 1.19 ± 0.05** | 0.79 ± 0.05# |
| LVIDd (mm) | 3.04 ± 0.1 | 3.11 ± 0.2 | 3.94 ± 0.3** | 3.18 ± 0.3*# |
| EF (%) | 75.5 ± 3.4 | 76.1 ± 5.5 | 58.2 ± 2.5** | 66.5 ± 3.7*## |
| HR (bpm) | 551.2 ± 44.4 | 567.5 ± 53.1 | 571.2 ± 47.2 | 561.2 ± 41.8 |
| LVESP (mmHg) | 98.2 ± 6.4 | 97.1 ± 5.5 | 82.6 ± 3.2** | 92.6 ± 6.9## |
| LVEDP (mmHg) | 1.7 ± 0.1 | 1.8 ± 0.1 | 7.7 ± 0.4** | 3.5 ± 0.3*# |
| Max dp/dt (mmHg/S) | 10116 ± 564.5 | 9946 ± 411.5 | 6018 ± 376.1* | 8287 ± 506.3*# |
| Min dp/dt (mmHg/S) | −8876 ± 334.6 | −8344 ± 504.1 | −5044 ± 207.6* | −6944 ± 343.8*# |
Note: LVAWd, left ventricular anterior wall end-diastolic thickness; EF, ejection fraction; LVIDd, left ventricular internal end-diastolic dimensions; HR, heart rate; LVESP, LV end-systolic pressur; LVEDP, LV end-diastolic pressure; max dp/dt, maximal contraction velocity; min dp/dt, maximal relaxation velocity; *p < 0.05, **p < 0.01 vs. respective sham mice. #p < 0.05, ##p < 0.01 vs. MI-vehicle mice.