Figure 6. Microscopic findings of fibrotic and condensed collagen-deposition areas in LV myocardium by day 5 after BD-derived tissue implantation.

(A–E) Illustrating the immunohistochemical (IHC) microscopic finding (200×) for identification of fibrotic area (blue color). (F) Analytical result for fibrotic area, ^* vs. other groups with different symbols (^†, ^‡, ^§), p < 0.0001. (G–K) Illustrating IHC microscopic finding (200×) for identification of condensed collagen-deposition area (pink color). (L) Analytical result of condensed collagen-deposition area, ^* vs. other groups with different symbols (^†, ^‡, ^§), p < 0.0001. The scale bars in right lower corner represent 50 µm. All statistical analyses were performed by one-way ANOVA, followed by Bonferroni multiple comparison post hoc test (n = 6). Symbols (^*, ^†, ^‡, ^§) indicate significance (at 0.05 level). NC = normal control; SC = sham control; BD_EX = brain death extract; Mel = melatonin; Luz = luzindole.