Table 2. Univariate and multivariate analyses of prognostic parameters for survival in 80 colorectal cancer patients.

	Univariate analysis			Multivariate analysis
Prognostic parameter	HR	95% CI	P value	HR	95% CI	P value
Expression of miR-27b (low vs. high)	0.437	0.226–0.845	0.014	0.448	0.224–0.896	0.023
Age ( < 65 vs. ≥ 65)	1.075	0.568–2.033	0.049	0.823	0.426–1.590	0.562
Gender (male vs. female)	1.131	0.596–2.147	0.707	-	-	-
Tumor Size ( ≤ 5 cm vs. > 5 cm)	2.384	1.216–4.677	0.012	1.999	1.001–3.992	0.050
CEA level (≤ 5 ng/ml vs. > 5 ng/ml)	1.207	0.624–2.333	0.576	-	-	-
Tumor location (rectum vs. colon)	1.189	0.624–2.266	0.599	-	-	-
TNM stage (I vs. II vs. III vs. IV)	1.827	1.300–2.566	0.001	1.683	1.181–2.399	0.004

HR: Hazard ratio; CI: Confidence interval. The bold number represents the P-values with significant differences.