Table 5. Top genes (FDR <0.1) in Yoruba and Cebu found using PrediXcan.
Chr. | Tissue | Gene name | Beta (Yoruba) | P (Yoruba) | FDR (Yoruba) | Beta (Cebu) | P (Cebu) | FDR (Cebu) | Beta (GLGC) | P (GLGC) |
---|---|---|---|---|---|---|---|---|---|---|
2p23.3 | THYROID | FNDC4 | 0.05 | 0.50 | 0.99 | −0.24 | 1.0 × 10−6 | 0.037 | −0.11 | 7.7 × 10−83 |
11p13 | ARTAORT | PAX6 | −0.74 | 4.8 × 10−7 | 0.093 | 0.16 | 0.20 | 0.98 | 0 | 0.91 |
11q23.3 | ESPMCS | BACE1 | 0.22 | 0.33 | 0.99 | −3.30 | 1.7 × 10−15 | 3.0 × 10−10 | −0.17 | 7.3 × 10−19 |
11q23.3 | CLNSGM | APOA4 | 0.80 | 0.55 | 0.99 | −11.6 | 6.5 × 10−12 | 5.9 × 10−7 | −1.95 | 1.7 ×10−39 |
11q23.3 | BRNHPP | APOA1 | 0.015 | 0.88 | 0.99 | 0.50 | 3.2 × 10−7 | 0.019 | 0 | 0.31 |
11q23.3 | HRTLV | SIDT2 | 0.24 | 0.21 | 0.98 | 0.90 | 8.1 × 10−7 | 0.037 | 0.16 | 9.3 × 10−29 |
11q23.3 | THYROID | SIDT2 | 0.10 | 0.61 | 0.99 | −0.55 | 1.7 × 10−6 | 0.050 | −0.55 | 1.1 × 10−102 |
11q23.3 | WHLBLD | BACE1 | 0.00 | 0.99 | 0.99 | −0.79 | 3.4 × 10−6 | 0.087 | −0.28 | 4.0 × 10−28 |