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. 2017 Dec 28;9(4):5216–5232. doi: 10.18632/oncotarget.23749

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Copyright: © 2018 Robb et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

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(A) IC₅₀ values from growth inhibition studies after CRC cells were treated with 20-223, AT7519 or Roscovitine for 72 hours. (B) Average IC₅₀ values across all seven CRC cell lines after treatment with 20-223, AT7519, or Roscovitine (P < 0.001). (C) Panel containing the seven CRC cell lines used in this study and mutational status of important regulatory genes.