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. Author manuscript; available in PMC: 2018 Feb 5.
Published in final edited form as: Shock. 2009 May;31(5):466–472. doi: 10.1097/SHK.0b013e31818ec47d

FIG. 2. Hypertonic saline decreases TNF-α–induced ICAM expression.

FIG. 2

A, Western blot of whole cell lysate does not find any ICAM-1 in unstimulated cells. TNF-α markedly increases ICAM-1 amounts. Hypertonic saline pretreatment alone does not induce ICAM-1 production. Hypertonic saline largely decreases the amount of TNF-α–induced ICAM-1 production. Vascular cell adhesive molecule 1 amounts are unchanged by TNF-α or HTS. B, Hypertonic saline significantly decreases TNF-α–induced ICAM-1 production. Densitometry data from four separate experiments are presented as SEM. Both the TNF-α–only group and the HTS/TNF-α group are significantly different from all other groups (*#P < 0.001).