Table 8. Study comparing PROMS between synthetic mesh (TiLOOP) and non-mesh reconstruction.

Reference	Methods/materials compared	Selection into cohort	Validated PROMS instrument used/subscales	Response rate	Follow-up period	Results	Comments
Dieterich et al [44], 2015	TiLOOP bra n = 42 Non-mesh – n = 42 Retrospective cohort	Specific selection into TiLOOP cohort was based on decision made intra-operatively	BREASTQ – post-reconstruction module (all subscales) – postal questionnaire, retrospective	67.7% NSD between two groups p = 0.117	TiLOOP 18 m (1–40) No mesh 17.5 m (1–83) P = 0.827	No significant differences between the groups in all of the domains. However, stepwise linear regression showed a negative association with “satisfaction with breasts” scores in the TiLOOP cohort	Surgeon selection into cohort and significant differences between two groups in terms of BMI and age