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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Microcirculation. 2018 Feb;25(2):10.1111/micc.12429. doi: 10.1111/micc.12429

Figure 4.

Figure 4

Impact of reduced gap junctional coupling on electrical conduction along resistance artery endothelium. (a) Representative simulation where the probability of gap junction connection between the two neighbor ECs is reduced from 100% (the control model) to 75%. (b) The resistance of individual EC-EC connections is reduced by half from the control Rgj of 4.5 MΩ in (a). In both panels the same hyperpolarizing current Istim = −1 nA was injected into a single EC at xstim = 100 μm. The one-dimensional short cable (Eq. 10) fit of the control profile from Figure 2a is also shown for reference to control conditions (dashed green line).