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. 2017 Aug 2;43(4):761–769. doi: 10.1038/npp.2017.141

Table 1. Reinforcing Effectiveness of Bath Salts Constituents MDPV, Methylone, and Caffeine Alone and in Binary Mixtures.

  MDPV : caffeine
Methylone : caffeine
MDPV : methylone
  EmaxSEM) Final ratio (±SEM) EmaxSEM) Final ratio (±SEM) EmaxSEM) Final ratio (±SEM)
Constituent 1 26.4 (1.0) 1168 (168) 14.8 (0.8) 118 (18) 26.3 (1.0) 1207 (177)
Constituent 2 8.7 (0.4) 27 (3) 8.3 (0.5) 24 (3) 18.1 (0.9) 271 (70)
10 : 1 Mixture 25.5 (0.8) 947 (156) 16.2 (0.7) 138 (20) 24.1 (1.5) 1007 (350)
3 : 1 Mixture 24.0 (0.7) 672 (76) 17.7 (1.0) 208 (38) 19.1 (0.6) 246 (34)
1 : 1 Mixture 21.6 (0.9) 445 (75) 16.6 (0.8) 157 (26) 18.6 (1.1) 266 (64)
1 : 3 Mixture 19.3 (0.6) 256 (30) 12.8 (0.4) 62 (6) 16.7 (0.9) 169 (36)