Table 1.

List of active and inactive compounds to open SiHsTRPA and AmHsTRPA channels

Active compounds to open SiHsTRPA	Inactive compounds to open SiHsTRPA	Active compounds to open AmHsTRPA	Inactive compounds to open AmHsTRPA
Fatty acids (C8, 1.32; C9, 1.619; C10, 1.596; C11, 1.93; C12, 1.991)	Fatty acids, C3-C7	Fatty acids (C8, 1.108; C9, 1.89; C10, 1.973; C11, 2.15; C12, 2.464)	3 mm menthol
Cinnamaldehyde (1.146)	Diallyl disulfide	Cinnamaldehyde (1.678)	0.5 mm carvacrol
β-Citronellal (1.704)	β-Citronellol	Diallyl disulfide (1.216)	α-Terpineol
β-Caryophelene (1.342)	Camphor	β-Citronellal (2.681)	2-Undecanone
	0.5 mm geranylacetone	β-Citronellol (1.634)	Terpinen-4-ol
	Eugenol	β-Caryophelene (3.228)	0.1% creosote
	Nerolidol	Camphor (1.421)	o-Methoxyphenol
	0.5 mm nerol	0.5 mm nerol (1.311)	2-Methoxy-4-methylphenol
	Thujone	Thujone (1.432)	N,N-diethyl-2-phenylacetamide
	Myrtenal	Nerolidol	Methyl salicylate
	β-Cyclocitral	0.5 mm geranylacetone	Verbenone
	2-Dodecanone	Eugenol	Coumarin
	2-Ethyl-1,3-hexanediol	Myrtenal	Thymol
	Methyl jasmonate	β-Cyclocitral
	3 mm menthol	2-Dodecanone
	0.5 mm carvacrol	2-Ethyl-1,3-hexanediol
	α-Terpineol	Methyl jasmonate
	2-Undecanone	Geraniol
	Terpinen-4-ol	Borneol
	Thymol	AITC
	2-Methoxy-4-methylphenol
	Geraniol
	o-Methoxyphenol
	Coumarin
	Verbenone
	0.1% Creosote; methyl salicylate; borneol; N,N-diethyl-2-phenylacetamide; AITC

All compounds were tested at 1-mm concentration except carvacrol, creosote, geranylacetone, nerol, and menthol, at the indicated concentrations. The average fold changes of Fura-2 ratio induced by active compounds shown in this report are indicated with parentheses.