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. 2017 May 30;21(2):135–143. doi: 10.1111/ner.12613

Table 1.

Evaluation of Treatment and Outcomes for Four of Six Patients Suffering Seizures.

Indication for DBS Onset of seizures Semiology Inter ictal EEG Ictal EEG Stimulation parameters at onset of seizures Fate of DBS
Patient 1 Poststroke pain (Haemorrhagic stroke on the right) 12 months Affective seizure (Psychic aura) and Speech arrest
Brought on by rapid ramping of stimulation
Intermittent, infrequent sharp transients over the frontocentral regions. Symmetrical frontal delta wave activity in long runs 3.5 mA
130 Hz
450 mics
Discontinued but felt to be worthwhile even at low settings
Patient 2 Poststroke pain (Right side stroke) 24 months
2 GTC seizure with suprathrehold stimulation in immediate postoperative period.
Loss of awareness with lip smacking
(Automotor seizures)
Two generalized tonic clonic seizures reported
Fast activity is prominent over the vertex No electrographic change 8 mA
130 Hz
450 mics
Discontinued
Patient 3 Postsurgical pain on the right following Spinal surgery for syringomyeila 12 months Left arm tonic seizures with speech arrest
Minor jerks in the left leg sometimes (Left leg myoclonic seizures)
Sharp transients are noted intermittently, maximal over both frontal regions, and occasionally focal in the right superior frontal area No electrographic change 6 mA
130 Hz
450 mics
Discontinued, then resumed (patient request)
Following management of seizures. Discontinued again following seizure recurrence
Patient 4 Whole spine pain‐failed back surgery 20 months Dialeptic (Behavioural arrest with loss of awareness) seizures with secondary generalization
(generalized seizures are nocturnal)
Sharp wave discharges are seen across the fronto‐central mid‐line with right sided emphasis Rhythmical, symmetrical 6 Hz theta slow wave activity across the fronto‐central regions that increments in amplitude and slows in frequency before ending abruptly 5V
130 Hz
450 mics
Discontinued, then resumed (patient request)
Following management of seizures.
PC&S device (see later in text) implanted.