Table 6. Two additional studies identified in systematic review of metformin and PCa risk and outcomes.
Author, year, country | Study design | No of patients | Main findings | Adjusted for |
---|---|---|---|---|
Haring, Finland, 2017 [75] | Cohort | 78,615 | Metformin decreased PCa incidence in a dose dependent manner (HR 0.81, 95%CI 0.69–0.95) | Age, trial arm, medications |
Haggstrom, Sweden, 2017 [74] | Cohort | 612,846 | Metformin did not decrease PCa incidence (HR 0.96 95%CI 0.77–1.19) | Age, education, CCI, county |