Fig 3. GP fluctuation following DENV infection of mosquito midguts.

(A) The metabolic pathway linking GP classes. Highlighted in bold are the GPs observed in this study. (B) GP landscape altered upon DENV infection in midguts. GP species that were altered on days 3, 7, and 11 pbm are listed by m/z and arranged by Log₂ fold changes from lowest to highest. A significant burst of GP abundance was observed at day 7 post-infection coinciding with increased viral replication in the midgut. (C) Heatmap of Log₂ fold changes of GP species on days 3, 7 and 11 arranged by putative ID subclasses. Abbreviations: CDP-DAG, cytidine diphosphate diacylglycerol; DAG, diacylglycerol; G-3-P, glyceraldehyde-3-phosphate; PA, phosphatidic acid; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PG, phosphatidylglycerol; PI, phosphatidylinositol; PS, phosphatidylserine.