Figure 4. Anti-miR-17 inhibited HCC cell proliferation and increased apoptosis.

A. H&E, IHC staining for cleaved caspase 3 (CC3) and phospho histone 3 (PH3) at 10X and 40X magnification from representative tumor samples from mice treated with control or anti-miR-17 therapy. B. Quantification of CC3 and pH3 staining by determining the average staining in five 40X magnification fields shows apoptosis is increased with anti-miR-17 therapy and proliferation is decreased.