Erratum to: Devoe DJ, Peterson A, Addington J. Negative Symptom Interventions in Youth at Risk of Psychosis: A Systematic Review and Network Meta-Analysis. Schizophr Bull. doi:10.1093/schbul/sbx139
The authors regret that, although the text is clear that neither efficacy nor effectiveness was statistically confirmed for any of the examined treatments, the abstract and text contained a mis-statement regarding effectiveness when rank ordering treatments according to the network analysis.
Page 1: In the Abstract under Results, Add “The null hypothesis was not rejected for any of the 11 treatments” between the first sentence “Of 3,027…. participants.” and the second sentence “Only N-methyl-D-aspartate-receptor (NMDAR) modulators trended towards a significant reduction in negative symptoms compared to placebo (SMD,-0.54, 95%CI, -1.09 to 0.02; I2 = 0%, P = 0.06).”
Page 1: In the Conclusion of the Abstract current wording should be deleted and the conclusions should now read: “Efficacy and effectiveness were not confirmed for any negative symptom treatment. Many studies had small samples and the majority were not designed to target negative symptoms.”
Page 9, line 18/19: Delete “…demonstrated small to large effect sizes for negative symptom reduction compared to ….” and replace with: “…ranked ahead of….”.
Page 9: Delete the last sentence of the NMDAR Modulators section line 33 and replace with: “Lastly, SUCRA plots of the absolute effects and rank test among the 11 treatments indicated that NMDAR modulators ranked higher than the other 10 treatments, but this is in the context of no statistically supported efficacy compared to placebo.”
Page 13: In the Conclusions of the main text the first sentence should be deleted and replaced with the following: “In conclusion, this review contained information on clinical trials of 11 treatment approaches. Support for efficacy or effectiveness did not reach statistical significance for any of the treatments. Many of the relevant studies had small samples…”.