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The Scientific World Journal logoLink to The Scientific World Journal
. 2009 Jan 18;9:5–9. doi: 10.1100/tsw.2009.6

Surgically Discovered Xanthogranulomatous Pyelonephritis Invading Inferior Vena Cava with Coexisting Renal Cell Carcinoma

Henry M Rosevear 1, Melissa M Meier 2, Brian L Gallagher 1, Fadi N Joudi 1,*
PMCID: PMC5823124  PMID: 19151892

Abstract

Xanthogranulomatous pyelonephritis (XGP) is a chronic inflammatory process that results in replacement of renal and/or perirenal tissue with a diffuse infiltrate of inflammatory cells referred to as xanthoma cells. We present a case of a 49-year-old man with an incidentally discovered renal mass with inferior vena cava (IVC) thrombus, who was found intraoperatively to have a significant inflammatory process involving the posterior wall of his IVC and right renal vein consistent with XGP surrounding a focus of clear cell renal cell carcinoma in the midportion of his right kidney.

Keywords: renal cell carcinoma, diagnostic imaging, xanthogranulomatous pyelonephritis


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