Table 4.
Characteristics of HCC patients between Portal Vein Thrombosis categories.
| Variables * | Portal Vein Thrombosis
|
||
|---|---|---|---|
| Negative | Positive | p# | |
| Sex (M) (%) | 959 (80.86) | 393 (82.91) | 0.33 ^ |
| Age (yrs) | 62.46±11.15 | 61.18±11.98 | 0.03 |
| Cigarettes smoke (%) | 316 (50.32) | 160 (54.42) | 0.24 ^ |
| Alcohol (%) | 97 (16.39) | 47 (16.43) | 0.99 ^ |
| Cirrhosis (%) | 917 (78.71) | 383 (84.36) | 0.01 ^ |
| HbsAg(+) (%) | 691 (60.14) | 293 (65.99) | 0.03 ^ |
| HCV(+) (%) | 229 (19.93) | 85 (19.14) | 0.72 ^ |
| Glucose (mg/dL) | 121.62±56.36 | 115.55±44.31 | 0.35 |
| Total Cholesterol (mg/dL) | 151.31±50.08 | 152.61±52.60 | 0.67 |
| LDL (mg/dL) | 95.25±41.90 | 101.43±44.76 | 0.11 |
| HDL (mg/dL) | 37.27±16.67 | 34.14±20.67 | 0.003 |
| Triglycerides (mg/dL) | 105.94±61.41 | 105.09±59.17 | 0.96 |
| MTD (cm) | 5.08±3.55 | 8.07±4.55 | <0.0001 |
| Nodules number (%) | <0.001 | ||
| 1 | 845 (72.28) | 215 (49.77) | |
| 2–3 | 322 (27.54) | 216 (50.00) | |
| >3 | 2 (0.17) | 1 (0.23) | |
| Hemoglobin (g/dL) | 12.48±2.25 | 12.07±2.24 | 0.001 |
| Hct (%) | 37.29±6.75 | 36.05±6.67 | 0.0005 |
| Platelet counts (103/μL) | 153.74±95.34 | 176.71±110.25 | 0.0002 |
| Ferritin (ng/mL) | 262.90±510.74 | 282.80±366.39 | 0.002 |
| Creatinine (mg/dL) | 1.01±0.73 | 1.20±4.02 | 0.31 |
| HbA1c (mmol/mol) | 6.21±1.70 | 6.18±1.80 | 0.73 |
| Total Protein (g/dl) | 6.94±9.41 | 6.83±4.69 | 0.03 |
| Albumin (g/dL) | 3.12±0.75 | 2.97±0.69 | 0.0003 |
| PT (%) | 14.63±4.47 | 14.82±5.60 | 0.81 |
| INR | 1.47±4.58 | 1.35±0.53 | 0.23 |
| CRP (mg/L) | 12.32±22.85 | 21.17±34.01 | <0.0001 |
| AFP (IU/mL) | 2910.73±16801.27 | 9890.79±44862.11 | <0.0001 |
| ALKP (U/L) | 194.60±186.56 | 248.68±262.28 | 0.002 |
| GGTP (U/L) | 150.33±172.01 | 188.37±181.97 | <0.0001 |
| AST (U/L) | 113.59±216.89 | 113.24±106.04 | 0.005 |
| ALT (U/L) | 81.69±183.25 | 62.15±53.90 | 0.71 |
| Total Bilirubin (mg/dL) | 2.33±3.49 | 3.07±4.50 | 0.01 |
*
All values: Means±Standard Deviation as continuous; Frequences and percentage (%) as categorical.
¥
Wilcoxon rank-sum (Mann-Whitney) test;
^
Chi-square test.
Abbreviations: GGTP, gamma glutamyl transpeptidae; ALKP, Alkaline phosphatase; AFP, Alpha-fetoprotein; MTD, Maximum Tumor Diameter; HDL: High Density Lipoprotein Cholesterol; LDL: Low Density Lipoprotein Cholesterol; HbA1c, Glycated hemoglobin; HCT, Hematocrit; PT, Prothrombin Time; INR, International Normalized Ratio; CRP, C-Reactive Protein.