. 2016 Jan 12;149(2):586–597. doi: 10.1378/chest.15-1777

Table 2.

Additional Studies That Supported the Use of CPAP in Surgical Patients With OSA

Author	Study Type and Surgical Procedure	No.	Result
Ramirez et al, 2009⁵²	Retrospective review Roux-en-Y gastric bypass	310	Postoperative CPAP vs no-CPAP: 91 vs 219 Basal atelectasis: 3.3% vs 1.8% (P > .05) Wound infection: 4.4% vs 0.45% (P > .05) GI bleeding: 0% vs 0.45% (NS) Overall morbidity: 4.5% vs 3.6% (P > .05)
Hallowell et al, 2007⁵⁰	Retrospective review Bariatric surgery	890	Selective OSA testing (1998-2003) vs mandatory OSA testing and perioperative CPAP Rx (2004-2005) Respiratory-related ICU stay 34% vs 9% (P < .001)
Meng et al, 2010⁴⁸	Retrospective review Roux-en-Y gastric bypass	356	Perioperative CPAP (102) vs no-CPAP (254) Nausea in PACU: 36% vs 35% (P = .91) Emesis in PACU: 19% vs 17% (P = .8) Hypertension: 18% vs 29% (P = .013) O₂ disturbance: 5% vs 13% (P = .012) PACU stay: 159 ± 78 vs 211 ± 82 (P = .029) Reintubation: 2% vs 5% (P = .45) ICU admission: 2% vs 5% (P = .45)
Neligan et al, 2009⁴⁹	RCT	40	Postextubation CPAP vs PACU CPAP FEV₁: coefficient, 0.37; SE, 0.13; P < .003; 95% CI, 0.13-0.62 FVC: coefficient, 0.39; SE, 0.14; P < .006; 95% CI, 0.11-0.66 PEFR: coefficient, 0.82; SE, 0.31; P < .008; 95% CI, 0.21-0.1.4
Huerta et al, 2002⁵¹	Prospective review Roux-en-Y gastric bypass	1067	No correlation between CPAP use and anastomotic leak (P = .06)

PACU = postanesthesia care unit; PEFR = peak expiratory flow rate. See Table 1 legend for expansion of other abbreviations.