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. 2018 Jan 30;40(1):71–72. doi: 10.1007/s11357-018-0007-1

Correction to: Age at menarche and age at natural menopause in East Asian women: a genome-wide association study

Jiajun Shi 1, Ben Zhang 1, Ji-Yeob Choi 2,3,4, Yu-Tang Gao 5, Huaixing Li 6, Wei Lu 7, Jirong Long 1, Daehee Kang 2,3,4, Yong-Bing Xiang 5, Wanqing Wen 1, Sue K Park 2,3,4, Xingwang Ye 6, Dong-Young Noh 8, Ying Zheng 7, Yiqin Wang 6, Seokang Chung 2, Xu Lin 6, Qiuyin Cai 1, Xiao-Ou Shu 1,
PMCID: PMC5832656  PMID: 29383570

Correction to: AGE (2016) 38:513–523

10.1007/s11357-016-9939-5

The original version of this article unfortunately contained a mistake.

The authors regret to inform the readers of a mistake in Table 4 regarding non-effect allele frequencies, which were presented as effect allele frequencies. The correct EAFs should be the originally presented numbers deducted from 1. For example, the EAF for rs4246511 is 0.39 in the originally published version, and the correct value is 0.61(=1–0.39). The correct table is given in this article.

Table 4.

Evaluation of GWAS-identified single nucleotide polymorphisms for age at natural menopause in East Asian women

Locus SNP Chr Base positiona Nearby gene Allelesb EAF SGWAS (n = 3556) Stage II (n = 3197) Combined (n = 6753) Dir
Beta (SE) P Beta (SE) P Beta (SE) P_METAL P_het
1 rs4246511 1 39,380,385 RHBDL2 T/C 0.61 0.247 (0.089) 0.006 0.303 (0.115) 0.008 0.268 (0.071) 1.4 × 10−4 0.699 +
2 rs1635501 1 242,040,775 EXO1 T/C 0.77 −0.025 (0.1) 0.807 −0.051 (0.128) 0.689 −0.035 (0.079) 0.661 0.869
3 rs2303369 2 27,715,416 FNDC4 T/C 0.13 0.065 (0.123) 0.597 0.117 (0.162) 0.471 0.084 (0.098) 0.391 0.801
4 rs10183486 2 171,990,971 TLK1 T/C 0.07 −0.029 (0.157) 0.855 −0.557 (0.222) 0.012 −0.204 (0.128) 0.111 0.052 +
5 rs7606918 2 172,895,449 MAP1D A/G 0.87 −0.097 (0.127) 0.443 0.308 (0.172) 0.074 0.045 (0.102) 0.657 0.058 +
6 rs4693089 4 84,373,622 HEL308 A/G 0.33 −0.107 (0.089) 0.230 −0.218 (0.115) 0.058 −0.149 (0.071) 0.035 0.447 +
7 rs890835 5 175,956,271 RNF44 A/C 0.24 −0.111 (0.099) 0.259 −0.063 (0.126) 0.615 −0.093 (0.078) 0.231 0.764
8 rs365132 5 176,378,574 UIMC1 T/G 0.52 0.229 (0.086) 0.008 0.125 (0.108) 0.245 0.189 (0.067) 0.005 0.450 +
9 rs2153157 6 10,897,488 SYCP2L A/G 0.68 0.165 (0.089) 0.065 −0.068 (0.115) 0.551 0.077 (0.071) 0.276 0.109 +
10 rs1046089 6 31,602,967 BAT2 A/G 0.40 −0.04 (0.086) 0.640 −0.101 (0.166) 0.543 −0.053 (0.076) 0.487 0.745 +
11 rs2517388 8 37,977,732 ASH2L T/G 0.35 0.014 (0.091) 0.876 −0.165 (0.115) 0.150 −0.055 (0.071) 0.443 0.220 +
12 rs12294104 11 30,382,899 Intergene T/C 0.10 0.052 (0.158) 0.742 −0.202 (0.257) 0.431 −0.018 (0.134) 0.896 0.399 +
13 rs2277339 12 57,146,069 PRIM1 T/G 0.77 0.181 (0.116) 0.118 0.290 (0.167) 0.082 0.216 (0.095) 0.023 0.592 +
14 rs3736830 13 50,306,221 KPNA3 C/G 0.37 −0.032 (0.088) 0.718 0.050 (0.113) 0.657 −0.001 (0.070) 0.991 0.568 +
15 rs4886238 13 61,113,739 TDRD3 A/G 0.04 −0.086 (0.23) 0.708 −0.041 (0.324) 0.899 −0.071 (0.188) 0.705 0.909
16 rs7333181 13 112,221,297 Intergene A/G 0.04 −0.147 (0.266) 0.580 0.194 (0.349) 0.580 −0.022 (0.212) 0.917 0.438 +
17 rs2307449 15 89,863,928 POLG T/G 0.64 0.210 (0.087) 0.015 0.006 (0.113) 0.955 0.134 (0.069) 0.050 0.153 +
18 rs10852344 16 12,016,919 Intergene T/C 0.15 −0.065 (0.122) 0.598 0.027 (0.162) 0.867 −0.031 (0.098) 0.749 0.651 +
191 rs11668344 19 55,833,664 TMEM150B A/G 0.91 0.659 (0.145) 5.6 × 10−6 0.247 (0.218) 0.257 0.533 (0.121) 1.0 × 10−5 0.115 +
192 rs12461110 19 56,320,663 NLRP11 A/G 0.29 −0.246 (0.092) 0.008 0.157 (0.136) 0.248 −0.119 (0.076) 0.117 0.014 +
20 rs16991615 20 5,948,227 MCM8 A/G 0.01 −2.783 (1.745) 0.111 −0.655 (1.425) 0.646 −1.506 (1.103) 0.172 0.345

SNP single nucleotide polymorphism, Chr chromosome, EAF Effective allele frequency, SE standard error, P_METAL P value from meta-analysis using METAL, P_het P value from between-study heterogeneity test, Dir allelic association direction compared to that from previous GWAS (“+” denotes same and “-” denotes opposite).

aChromosome position based on NCBI human genome build 37 from the 1000 Genomes Project

bShown as effect allele/other allele

Footnotes

The online version of the original article can be found at 10.1007/s11357-016-9939-5


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