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(A–C) Protein and mRNA expressions of Nr4a2 were significantly elevated after transfection with Nr4a2-overexpressing plasmid in CD4+ T cells from patients with PV (p = 0.0192, p = 0.001, respectively). (D) mRNA expression levels of GATA3, IL-4, and IL-13 were significantly decreased after transfection with Nr4a2-overexpressing plasmid in CD4+ T cells from patients with PV (p < 0.001; p < 0.001, p < 0.001, respectively). (*p < 0.05, **p < 0.01, ***p < 0.001).
