Fig. 3.

Overview of lean-abdominally obese differences in expression of genes related to (left) oxidative phosphorylation and (right) carbohydrate metabolism in PBMCs at fasting (T0) and during postprandial response (∆ lean vs. ∆ abdominally obese postprandial) to a mixed meal challenge. Also shown are effects of WL on gene expression in PBMCs of abdominally obese subjects at baseline (abdominally obese after WL vs. abdominally obese before WL) and during postprandial phase (∆ abdominally obese after WL vs. ∆ abdominally obese before WL). The heatmap is based on moderated t-statistics for each comparison, which has the same interpretation as an ordinary t-statistic except that the standard errors have been moderated across genes using a simple Bayesian model