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. 2018 Jan 10;9(11):9940–9950. doi: 10.18632/oncotarget.24119

Figure 5. CXCR4 and CXCL12 expression on paraffin-embedded sections of a representative vestibular schwannoma sample.

Figure 5

(A) CXCR4 (green) co-localizes with the Schwann cell/tumor marker S100 (red). (B) CXCR4 (green) does not co-localize with CD68 (red), a macrophage marker, indicating that these cells do not express CXCR4. (C) CXCL12 (green) co-localizes with S100 (red) but (D) not with CD68 (red) in the main part of the tumor. E and F) Although healthy vestibular nerves obtained from autopsies show positive S100 (red) staining, they show no significant CXCR4 or CXCL12 expression (green). Scale bar, 50 µm.