Table 1.

Baseline characteristics of patients in the IeDEA HIV-2 Cohort according to sex from 2002 to 2014

Baseline characteristics	HIV-2 infected patients initiating ART
	Men		Women		Total		P*
	723	(39.6%)	1 102	(60.4%)	1 825	(100%)
Age years, median (IQR)	48.8 [42.9 – 54.6]		42.6 [35.9 – 49.8]		45.4 [38.0 – 52.0]		0.000
16–39	131	18.1	437	39.7	568	31.1
40–49	288	39.8	396	35.9	684	37.5
≥50	304	42.1	269	24.4	573	31.4
WHO Clinical stage n (%)							0.180
I and II	261	36.1	402	36.5	663	36.3
III and IV	97	13.4	117	10.6	214	11.7
Missing	365	50.5	583	52.9	948	52.0
Initial CD4 cell count, median (IQR) cells/mm3	160 [79 – 262]		204 [105 – 337]		185 [95 – 297]		0.000
0 – 49	73	10.1	86	7.8	159	8.7
50 – 99	88	12.2	99	9.0	187	10.2
100 – 199	148	20.5	201	18.2	349	19.1
200 – 349	136	18.8	227	20.6	363	19.9
≥350	60	8.3	179	16.2	239	13.1
Missing	218	30.2	310	28.1	528	28.9
Initial ART regimen							0.018
PI-based regimen	507	70.1	709	64.3	1216	66.6
Triple NRTI-based regimen	68	9.4	105	9.5	173	9.5
Sub optimal ART regimen**	148	20.5	288	26.2	436	23.9
BMI, median (IQR) Kg/m2							0.015
<18	88	12.2	103	9.3	191	10.4
18 – 25	199	27.5	273	24.8	472	25.9
>25	52	7.2	117	10.6	169	9.3
Missing	384	53.1	609	55.3	993	54.4
Haemoglobin level n (%) g/dL							0.000
<7.5	51	7.1	81	7.4	132	7.2
7.5 – 9.9	98	13.5	216	19.6	314	17.21
10 – 12	134	18.5	266	24.1	400	21.9
>12	168	23.2	128	11.6	296	16.2
Missing	272	37.6	411	37.3	683	37.4
Year of ART initiation							0.000
<2007	249	34.4	277	25.1	526	28.8
2007–2010	201	27.8	345	31.3	546	29.9
2011–2014	273	37.8	480	43.6	753	41.3

IQR: Interquartile Range; ART: Antiretroviral therapy; BMI: Body mass index; Hb: Haemoglobin; p*: p-value indicating a significant difference between men and women for the considered variable;

^**Sub optimal regimen indicative of patients initially miss-diagnosed and treated as HIV-1.