Table 4. Genes involved in spindle assembly and segregation.

Gene symbol	Common name (homolog)	Functiona	References
ncd	Kinesin family member C1	Bundles microtubules	Hatsumi and Endow (1992a); Matthies et al. (1996)
asp	Aspm	Microtubule-associated protein	Saunders et al. (1997); Riparbelli et al. (2002)
Klp54D	Kinesin family member 12	Spindle symmetry	Radford et al. (2017)
Klp61F	Kinesin family member 11	Spindle symmetry	Radford et al. (2017)
Klp10A	Kinesin-13	Spindle assembly	Zou et al. (2008); Radford et al. (2012a); Do et al. (2014)
Eb1	Mapre family	Microtubule binding	Do et al. (2014)
aurB	Aurora Kinase B	Chromosomal passenger complex; spindle midzone	Radford et al. (2012b)
Incenp	Incenp	Chromosomal passenger complex; spindle midzone	Colombie et al. (2008); Radford et al. (2012b)
sub	MKLP-2/kinesin 6	Spindle midzone	Giunta et al. (2002); Jang et al. (2005); Radford et al. (2017)
tum	RacGAP50C	Centralspindlin complex; spindle midzone	Das et al. (2016)
mei-38	TPX2	Promotes kinetochore microtubules	Baker and Carpenter (1972); Wu et al. (2008)
msps	XMAP215/TOG	Maintains bipolarity	Cullen and Ohkura (2001)
cks30A	CKs/Suc1	Spindle assembly	Cullen et al. (2005)
d-tacc	D-TACC	Maintains bipolarity	Cullen and Ohkura (2001)
α-Tub67C	Maternally loaded α-tubulin	Microtubule nucleation	Matthies et al. (1999)
γ-Tub37C	γ-tubulin	Microtubule nucleation	Tavosanis et al. (1997); Hughes et al. (2011)
Augmin complex		Chromosome alignment and movement	Meireles et al. (2009); Colombie et al. (2013)
Grip71	γTurc complex	Microtubule nucleation	Reschen et al. (2012)
Sentin/ ssp2		Kinetochore attachment to microtubules	Gluszek et al. (2015)
rod	Kntc1	Rzz complex; spindle assembly checkpoint	Gluszek et al. (2015)
Top2	Topoisomerase 2	Chromosome orientation	Hughes and Hawley (2014)
nod	Nonmotile member of kinesin family	Polar ejection force; chromosome alignment	Baker and Carpenter (1972); Zhang and Hawley (1990); Zhang et al. (1990); Theurkauf and Hawley (1992); Hughes et al. (2009)
Axs	Ano family	Spindle width; achiasmate chromosome segregation	Zitron and Hawley (1989); Kramer and Hawley (2003a)
mps1/ald	Mps1	Meiotic spindle assembly checkpoint; chromosome segregation	O’Tousa (1982); Gilliland et al. (2005), (2007)
cnn	Centrosomin	Central aster of meiosis II spindles	Riparbelli and Callaini (2005)
Grip75	γTurc Complex	Meiosis II spindle assembly	Vogt et al. (2006)
Grip128	γTurc Complex	Meiosis II spindle assembly	Vogt et al. (2006)
Mud	NuMa	Meiosis II central aster	Yu et al. (2006)
sra	RCAN	Meiosis II entry; oocyte activation	Horner et al. (2006); Takeo et al. (2006); (2010)
canB2	calcineurin regulatory subunit B	Meiosis II entry; oocyte activation	Takeo et al. (2010)
mei-S332	Shugoshin	Protection of centromeric cohesion	Kerrebrock et al. (1992), (1995)
cort	Cortex	APC; Meiosis II progression; egg activation	Page and Orr-Weaver (1996); Whitfield et al. (2013)
grau	Grauzone	Meiosis II progression; egg activation; destruction of proteins	Page and Orr-Weaver (1996)
fzy	Cdc20 (APC)	Meiosis II progression; destruction of proteins	Swan and Schupbach (2007)

APC, anaphase-promoting complex.

^aMost likely function based on genetic, biochemical, or cytological data.