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. 2018 Jan 30;9(15):12137–12153. doi: 10.18632/oncotarget.24343

Figure 6. Apoptosis in IR-injured retinas after overexpression of let-7d by agomir.

Figure 6

(A) The percentage of activated caspase-3-positive cells (red) in GCLs of IR-injured retinas after let-7d overexpression. (B) Bcl-2/Bax ratios and activated caspase-3 in IR-injured retinas were evaluated by western blot analysis after let-7d overexpression. (C) Densitometric analysis of expression of activated caspase-3 in IR-injured retinas after let-7d overexpression. (D) Densitometric analysis of Bcl-2/Bax ratios in IR-injured retinas after let-7d overexpression. n = 8, ####p < 0.0001, versus control; ****p < 0.0001, versus vehicle; ns: no significance.