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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Nanomedicine. 2017 Oct 24;14(2):397–404. doi: 10.1016/j.nano.2017.10.004

Figure 2. Enhancement mouse cochlea MR image using a Gadolinium contrast agent.

Figure 2

Mouse cochlear structures in MPR multi view of T1-weighted images with IT administration of Gd-DOTA (23 mm coil) (180 min time point). Gelfoam soaked with 5 μL, 500 mmol/L Gd-DOTA was placed into the left ear. In the enlarged window A, LW and Mod are slightly highlighted by Gd-DOTA uptake in addition to more pronounced enhancement in ST and SV. The structure adjacent to ST is suspected to be CA with signal intensity similar to ST. LW demonstrated brighter signal than SM. A dark border appeared between ST and LW in the basal turn near the hook region. OSL is seen as a sharp dark line. Small window B is a relative perpendicular cut through the center of plane A. Small window C is a relative axial cut through the center of the cochlea in window A. Small window D is the minimized image of window A. CA, cochlear aqueduct; LW, lateral wall; Mod, modiolus; MPR, multiplanar reconstruction; OSL, osseous spiral lamina; SM, the scala media; ST, the scala tympani; SV, the scala vestibuli; 1st, the basal turn; 2nd, the second turn. Reprinted from Zou et al (2010)67.