Fig. 9. A decision tree built from a large number of Draize eye irritation tests.

In the Draize test, several features of the exposed animal eye are measured including cornea damage, conjunctivae damage, irreversibility of the observed damage and a few others. The decision tree built from the hundreds of Draize eye irritation tests closely matches the OECD guidelines (reproduced from Luechtefeld et al., 2016b).