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. 2008 Dec 25;8:1325–1327. doi: 10.1100/tsw.2008.164
Inhibition of Steroid Sulfatase Activity in Endometriotic Implants by STX64 (667Coumate): A Potential New Therapy
L Fusi
1, A Purohit
2, J Brosens
1, L W L Woo
3, B V L Potter
3, M J Reed
2,*
L Fusi
1
Institute of Reproductive and Developmental Biology,
Imperial College London,
Hammersmith Hospital,
Du Cane Road, London, W12 0NN,
UK
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A Purohit
2
Endocrinology and Metabolic Medicine and Sterix Ltd.,
Imperial College London,
St. Mary's Hospital,
Praed Street, London,W2 1NY,
UK
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J Brosens
1
Institute of Reproductive and Developmental Biology,
Imperial College London,
Hammersmith Hospital,
Du Cane Road, London, W12 0NN,
UK
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L W L Woo
3
Medicinal Chemistry,
Department of Pharmacy and Pharmacology and Sterix Ltd.,
University of Bath,
Claverton Down, Bath, BA2 7AY,
UK
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B V L Potter
3
Medicinal Chemistry,
Department of Pharmacy and Pharmacology and Sterix Ltd.,
University of Bath,
Claverton Down, Bath, BA2 7AY,
UK
Find articles by B V L Potter
M J Reed
2
Endocrinology and Metabolic Medicine and Sterix Ltd.,
Imperial College London,
St. Mary's Hospital,
Praed Street, London,W2 1NY,
UK
Find articles by M J Reed
1
Institute of Reproductive and Developmental Biology,
Imperial College London,
Hammersmith Hospital,
Du Cane Road, London, W12 0NN,
UK
2
Endocrinology and Metabolic Medicine and Sterix Ltd.,
Imperial College London,
St. Mary's Hospital,
Praed Street, London,W2 1NY,
UK
3
Medicinal Chemistry,
Department of Pharmacy and Pharmacology and Sterix Ltd.,
University of Bath,
Claverton Down, Bath, BA2 7AY,
UK
✉
*M. J. Reed: b.v.l.potter@bath.ac.uk
Academic Editor: Martin Goette
Received 2008 Aug 20; Revised 2008 Dec 10; Accepted 2008 Dec 17; Collection date 2008.
Keywords: endometriosis, steroid sulfatase, steroid sulfatase inhibitors, STX64, 667Coumate
Copyright © 2008 L. Fusi et al.
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
PMCID: PMC5849069 PMID: 19112542