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Characteristics of twin and sibling cohort (37 pairs, n=74 subjects). S.D., standard deviation; BMI, body mass index; Hgb, hemoglobin.
| Parameter | Cases (n = 21) [with NAFLD] | Controls (n = 53) [without NAFLD] | P-value |
|---|---|---|---|
| Age (S.D.) | 52.1 (19.6) | 46.1 (20.6) | 0.26 |
| % Male | 57 | 32 | 0.07 |
| % Caucasian | 67 | 51 | 0.30 |
| % Hispanic | 24 | 15 | 0.27 |
| BMI (S.D.) | 32.3 (5.0) | 27.2 (5.4) | < 0.001 |
| Hgb A1c (S.D.) | 6.1 (0.7) | 5.7 (0.4) | 0.001 |
| ALT (S.D.) | 30 (18) | 21 (12) | 0.01 |
| MRI-PDFF (S.D.) | 10.7 (5.4) | 2.6 (0.9) | < 0.0001 |
