Addendum to: Nature Communications 10.1038/s41467-017-00698-y, published online 21 September 2017
We would like to make our readers aware of the publication by Alvarez-Castelao et al., which reports the original development of the Floxed MetRS L274G mice for the cell-specific labelling of proteins in vivo and provides an in-depth characterisation of these mice1. Breeding pairs of Floxed mice were graciously donated by Erin Schuman and coworkers well in advance of the publication by Alvarez-Castelao et al. Application of this technology to cell transplantation, selective identification of ‘young’ proteins in the setting of heterochronic parabiosis, and array proteomics was developed by the Conboy laboratory.
Footnotes
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References
- 1.Alvarez-Castelao B, et al. Cell-type specific metabolic labelling of nascent proteomes in vivo. Nat. Biotech. 2017;35:1196–1201. doi: 10.1038/nbt.4016. [DOI] [PubMed] [Google Scholar]