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Favipiravir inhibits infection of Asian ZIKV strains in hNPCs. hNPCs were infected with ZIKV PRVABC59 or ZIKV P6-740) at MOI of 1, and treated with either DMSO control (0 μM), favipiravir (1, 10, 25 μM) for 72 h after infection. Levels of ZIKV E and NS5 mRNA were measured in PRVABC59 or P6-740 infected hNPCs over time using qRT-PCR. * p < 0.05; ** p < 0.01, compared with DMSO control-treated cells.
