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. 2017 Nov 6;37(8):1086–1094. doi: 10.1038/onc.2017.383

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/

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DHRS2 downregulation was significantly associated with poorer prognosis of ESCC. (a) The representative pictures of DHRS2 staining in ESCC tumor tissue and paired non-tumor tissue. The boxed regions were magnified and shown in the right panels. (b) Kaplan–Meier analysis showed that DHRS2 downregulation was significantly associated with ESCC patients’ poorer survival. (c) The relative quantification of DHRS2-V1 and DHRS2-V2 in ESCC cell lines, NE1 (an immortalized human esophageal epithelial cell line) and non-tumor esophageal tissues pool (three cases).