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. 2018 Feb 8;10(2):186. doi: 10.3390/nu10020186

Figure 2.

Figure 2

Vitamin C regulates musculoskeletal genes in hBMSCs. Real-time PCR showing dose dependent change in gene expression in hBMSCS after vitamin C treatment (a) Collagen II; (b) BMP-2; (c) BMP-7; (d) RUNX2 and (e) OSX (Osterix). Data (n = 4) are represented as the fold change in expression compared with control (* p = 0.04, # p = 0.001); (f) Intracellular concentration of vitamin C in hBMSCs. hBMSCs cells were treated with 100 μM vitamin C and intracellular accumulation of vitamin C was measured in the control and vitamin C treated cells after 6hrs (n = 6, # p = 0.001).