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. 2018 Feb 12;8(6):1740–1751. doi: 10.7150/thno.22010

Figure 2.

Figure 2

Signaling pathways altered by somatic mutations in HCC. Red and blue colors denote SMGs with predicted activating and inactivating mutation, respectively. Genes in white color are not SMGs but have key roles in tumorigenesis. Druggable targets are marked with red stars. Note: For TERT, promoter instead of exomic region mutation frequency is shown.