Table 1.

Multivariate Cox regression analysis for overall survival

		Univariate analysis			Multivariate analysis
Variables		Hazard Ratio (95% CI)	p-value		Hazard Ratio (95% CI)	p-value
Age	Older than 65	1.13 (0.83 - 1.53)	0.45
Stage	≥III	2.62 (1.91 - 3.60)	<0.0001		2.31 (1.67 - 3.20)	<0.0001
TMI	Hypermetabolic tumor	1.61 (1.19 - 2.19)	0.002		1.23 (0.85 - 1.77)	0.27
Microenvironment cell type clusters	C2	0.58 (0.38 - 0.89)	0.01		0.63 (0.40 - 1.01)	0.05
	C3	0.90 (0.59 - 1.37)	0.61		0.83 (0.53 - 1.29)	0.41
	C4	0.62 (0.38 - 1.01)	0.05		0.82 (0.48 - 1.38)	0.45
ImmuneScore	High ImmuneScore	0.65 (0.48 - 0.88)	0.005		0.69 (0.48 - 0.98)	0.04
Molecular Subtypes	Magnoid	1.99 (1.35 - 2.92)	0.0005		1.42 (0.93 - 2.18)	0.11
	Squamoid	1.84 (1.29 - 2.62)	0.0008		1.46 (0.96 - 2.22)	0.08

CI: confidence interval