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Tissue uptake of FA-PTX-EB and PTX-EB. MDA-MB-231 tumor xenografts at 4 h post-injection of EB-conjugated PTX prodrugs. Tissues (liver, kidneys, and tumor) were immediately excised for sectioning and were visualized by fluorescence microscopy. The red fluorescence from EB-conjugated compounds (A) and corresponding flow cytometry values (B) were observed in liver, kidneys and tumor, respectively. Data represent mean ± standard deviation (SD), n = 5/group.
