We found that for Class I epitope prediction data, different HLA–A, −B, and −C alleles account for 51.59% of the variation in epitopes predicted to bind (F = 10.55, p<0.0001) while the specific vaccine or control protein analyzed accounts for 23.52% of the variation (F = 84.16, p<0.0001). For the Class II predictions, different HLA-DRB1 alleles account for 66.55% of the variation in epitopes predicted to bind (F = 37.29, p<0.0001) while the specific vaccine or control protein analyzed accounts for 24.52% of the variation (F = 90.70, p<0.0001).
Footnotes
Competing Interests: No competing interests declared.