. 2018 Feb 7;9(18):14354–14365. doi: 10.18632/oncotarget.24436

Table 2. Candidate mRNAs in tissues^*.

Gene symbol	Tissue mRNA array	Tissue real-time PCR expression data
	(normal vs. BC)		Normal controls	BC
	P-value	-fold change	(expression level, × 10⁴ copies/μg) Median (IQR)^a	(expression level, × 10⁴ copies/μg) Median (IQR)^a	P-value^b
CDC20	0.001	3.9323197	6.2 (2.8–19.8)	32.0 (9.0–77.2)	0.011
IQGAP3	0.001	3.3673384	2.6 (1.6–10.4)	86.6 (32.6–201.9)	<0.001
TOP2A	0.001	3.2166836	6.7 (3.8–24.6)	428.0 (143.3–1030.3)	<0.001
UBE2C	0.001	2.9033677	111.9 (82.8–140.7)	340.1 (161.5–643.6)	0.003

^* These tissue mRNAs were chosen because they showed the greatest increase in expression in bladder cancer tissue compared with control tissue in microarrays.

IQR, interquartile range; BC, bladder cancer.

^a Copy number of corresponding transcripts (per μg of total RNA) used for cDNA synthesis.

^b Mann-Whitney U test.

Table 2. Candidate mRNAs in tissues*.

Table 2. Candidate mRNAs in tissues^*.