Video 11. Functional consequence of disrupted Nlg1 signalling; Nlg1 GOF.
GCaMP6m was used as a proxy to explore the effect of disrupted Nlg1 signalling on late-stage postsynaptic activity. Nlg1 overexpression in muscles results in heterogenous muscle calcium activity, with subsets of muscles firing more frequently than others (Mef2-GAL4 > GCaMP6m + Nlg1untagged). Frames recorded at 1 s intervals. Time format mm:ss.