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. 2018 Jan 6;73(4):376–384. doi: 10.1136/thoraxjnl-2017-210947

Table 4.

Associations between vigorous physical activity variables at the first examination and lung function and decline*

Vigorous physical activity levels N FEV1 (mL) FVC (mL)
Mean difference 95% CI N Mean difference 95% CI
Association with lung function†
Frequency
 ≤1 a month 3887 Reference 3872 Reference
 1–3 times a week 13.2 −20.3 to 46.6 16.9 −21.2 to 55.1
 ≥4 times a week 12.3 −35.9 to 60.4 59.3 4.4 to 114.3
Duration (per week)
 ≤30 min 3857 Reference 3842 Reference
 1–3 hours 20.8 −13.2 to 54.8 13.5 −25.3 to 52.3
 ≥4 hours 39.3 −5.9 to 84.6 73.9 22.4 to 125.4
Active
 ≥2 times and ≥1 hour per week 3855 43.6 12.0 to 75.1 3840 53.9 17.8 to 89.9
Association with rate of lung function decline‡
Frequency
 ≤1 a month 3887 Reference 3872 Reference
 1–3 times a week 1.6 −0.3 to 3.4 0.1 −2.2 to 2.5
 ≥4 times a week −0.3 −2.9 to 2.4 −1.5 −4.9 to 2.0
Duration   (per week)
 ≤30 min 3857 Reference 3842 Reference
 1–3 hours 2.3 0.4 to 4.1 1.7 −0.7 to 4.1
 ≥4 hours 1.4 −1.1 to 3.9 1.9 −1.4 to 5.1
Active
 ≥2 times and ≥1 hour per week 3855 1.4 −0.3 to 3.2 3840 −0.3 −2.6 to 2.0

Bold indicates P value <0.05.

*Adjusted for sex, age, age-squared, height, weight, smoking status, second-hand smoke exposure, education and occupation. An interaction term between time between follow-ups and the physical activity parameter was included to capture the effect of physical activity on lung function decline.

†A positive estimate suggests that those more active at the first examination had higher average lung function at both examinations than those less active.

‡A positive estimate suggests that those more active at the first examination had a smaller decline in lung function between the two examinations than those less active.

N, number of participants included in the model.