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Paramecium Dicer-like Cleavage Preferences and the Role of sRNA End Sequence Bias during DNA Elimination Process
(A) A Neighbor-Joining phylogenetic tree of Paramecium Dicer-like enzymes and a summary of their sequence and length preferences.
(B) A schematic of iesRNA-guided IES excision. Sequence cleavage preference of Dcl5 leads to the production of iesRNAs, which match preferentially to IES ends, thus enabling their precise excision.
