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. 2018 Feb 26;10(3):266. doi: 10.3390/nu10030266

Figure 2.

Figure 2

Distribution of genetic risk scores (GRS) and within-group changes in body fat as a function of changes in diet or exercise regime. Each individual’s GRS can be calculated based on the final set of SNPs to measure changes in carbohydrate intake (CE), fat intake (FE), total calorie intake (TE), and exercise status (EE). To determine the effectiveness of body fat loss, “very low” (VL) was defined to range from the minimum of GRS and the value less than the 25th percentile. The “low” (L) level ranges from the value larger than or equal to the 25th percentile and 50th percentile, “high” (H) includes values larger than or equal to the 50th percentile and less than the 75th percentile, and “very high” (VL) corresponds to values larger than or equal to the 75th percentile. Among individuals with greater than 75 g reduction in carbohydrate intake, the mean change in body fat in individuals grouped to CE-VL was 0.13, −0.37 for the group CE-L, −0.54 for the CE-H group, and −1.19 for the CE-VH group. Among individuals with at least 13 g reduction in fat intake, the mean changes in body fat were −0.22, −0.095, −0.25, and −0.80 for the groups FE-VL, FE-L, FE-H, and FE-VH, respectively. Among individuals with at least 478 kcal reduction in total calorie intake, the mean changes in the body fat were 0.093, 0.0055, −0.64, and −1.14 for the groups TE-VL, TE-L, TE-H, and TE-VH, respectively. Among individuals who experienced exercise onset, the mean changes in body fat were 0.92, 0.41, −0.033, and −0.018, respectively.