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. 2017 Oct;7(5):379–380. doi: 10.1212/01.CPJ.0000526703.18435.da

Anton syndrome as a result of MS exacerbation

Nitin K Sethi 1
PMCID: PMC5874475  PMID: 29620069

I read with interest the case report by Kim et al.1 detailing Anton syndrome (AS) in a patient with multiple sclerosis. Apart from visual anosognosia, confabulation is an important symptom of AS. It is important to remember that AS on occasion may be associated with Charles Bonnet syndrome characterized by visual loss and hallucinations. Apart from imaging, cortical blindness with preserved pupillary reaction to light and accommodation, intact ocular movements, normal optic fundi, absent visual evoked potential, and absent optokinetic nystagmus may all aid in securing a clinical diagnosis of AS.2,3

Disclosures:

N. Sethi serves as Associate Editor of The Eastern Journal of Neurology.

Neurol Clin Pract. 2017 Oct;7(5):379–380.

Author Responds:

Nina H Kim 1

We thank Dr. Sethi for his interest in our case report.1 Cortical blindness can be ascertained by the examinations that Dr. Sethi highlights. It is also important that the patient is able to speak (and confabulate) to determine the diagnosis. AS is considered to be one of the disconnection syndromes that results in the fascinating phenomena of confabulation.

Disclosures:

N. Kim holds stock/stock options in Natus.

References

  • 1.Kim N, Anbarasan D, Howard J. Anton syndrome as a result of MS exacerbation. Neurol Clin Pract 2017;7:e19–e22. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Zuki S, Sinanovi O, Zoni L, Hodi R, Mujagi S, Smajlovi E. Anton's syndrome due to bilateral ischemic occipital lobe strokes. Case Rep Neurol Med 2014;2014:474952. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Misra M, Rath S, Mohanty AB. Anton syndrome and cortical blindness due to bilateral occipital infarction. Indian J Ophthalmol 1989;37:196. [PubMed] [Google Scholar]

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