. 2018 Feb 26;9(20):15168–15179. doi: 10.18632/oncotarget.24586

Table 1. Baseline characteristics of patients, tumor and surgery.

	<40 y n = 1453		40−50 y n = 3420		51−65 y n = 3510		>65 y n = 566		all patients n = 8949		p value^*
	n	Valid %	n	Valid %	n	Valid %	n	Valid %	n	Valid %	p value^*
Tumor stage											<0.001
cT1	135	9.4	283	8.3	192	5.5	24	4.3	634	7.1
cT2	984	68.3	2189	64.5	2175	62.4	310	55.3	5658	63.7
cT3	214	14.9	586	17.3	567	16.3	95	16.9	1462	16.5
cT4a-c	50	3.5	181	5.3	277	8.0	67	11.9	575	6.5
cT4d	57	4.0	153	4.5	272	7.8	65	11.6	547	6.2
Missing									73	0.8
Nodal status											0.031
N0	731	51.6	1670	49.7	1649	47.9	249	44.5	4299	49.0
N 1−3	619	43.7	1518	45.2	1578	45.8	272	48.6	3987	45.4
N 4−9	50	3.5	131	3.9	163	4.7	32	5.7	376	4.3
N >10	18	1.3	38	1.1	56	1.6	7	1.3	119	1.4
Missing									168	1.9
Histological type											<0.001
Ductal invasive	1221	85.7	2721	81.5	2720	79.0	439	77.6	7101	81.0
Lobular invasive	86	6.0	400	12.0	502	14.6	78	13.8	1066	12.2
Others	117	8.2	217	6.5	221	6.4	49	8.7	604	6.9
Missing									178	2.0
Tumor grade											<0.001
G1	42	3.1	137	4.2	119	3.6	17	3.1	315	3.7
G2	684	49.8	1812	55.6	1839	55.6	322	59.1	4657	54.9
G3	647	47.1	1312	40.2	1350	40.8	206	37.8	3515	41.4
Missing									462	5.2
ER status											<0.001
Negative	630	45.4	1244	37.8	1206	35.8	198	35.2	3278	38.1
Positive	758	54.6	2050	62.2	2160	64.2	365	64.8	5333	61.9
Missing									338	3.8
PR status											<0.001
Negative	700	50.5	1415	43.0	1611	48.0	284	50.5	4010	46.6
Positive	687	49.5	1878	57.0	1746	52.0	278	49.5	4589	53.4
Missing									350	3.9
HER-2 Status											0.072
Negative	829	72.1	2050	74.4	1974	74.2	371	78.4	5224	74.2
Positive	320	27.9	707	25.6	688	25.8	102	21.6	1817	25.8
Missing									1908	21.3
Molecular subtypes											<0.001
HR positive/HER2−	463	42.3	1309	49.2	1319	51.8	256	54.9	3347	49.5
HR positive/HER2+	174	15.9	419	15.8	358	14.1	54	11.6	1005	14.9
HR negative/HER2+	137	12.5	275	10.3	313	12.3	48	10.3	773	11.4
TNBC	320	29.3	655	24.6	555	21.8	108	23.2	1638	24.2
Missing									2186	24.4
BMI											<0.001
<18.5	42	2.9	63	1.9	30	0.9	3	0.5	138	1.6
18.5−24.9	895	62.0	1802	53.1	1377	39.7	189	33.4	4263	48.0
25.0−29.9	325	22.5	1009	29.7	1224	35.3	215	38.0	2773	31.2
30.0−39.9	163	11.3	480	14.1	784	22.6	145	25.6	1572	17.7
≥40	19	1.3	40	1.2	55	1.6	14	2.5	128	1.4
Missing									75	0.8
Surgery Type											<0.001
Breast conserving therapy	992	71.9	2321	70.7	2333	70.1	310	58.5	5956	69.9
Mastectomy	387	28.1	964	29.3	997	29.9	220	41.5	2568	30.1
Missing									425	4.7

* χ² or Fisher´s test.