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. Author manuscript; available in PMC: 2018 Apr 3.
Published in final edited form as: Hypertension. 2016 Sep 26;68(5):1123–1131. doi: 10.1161/HYPERTENSIONAHA.116.08046

Table 3.

Association of birth weight relative weight gain and linear growth in infancy and mid-childhood, and SBP trajectory groups between 5 and 18 years (OR, 95%CI, p value)

A. BOYS Model 1 Model 2 Model 3 Model 4

Middle vs Lower trajectory group OR 95%CI P value OR 95%CI P value OR 95%CI P value OR 95%CI P value

Birth weight(z score) 1.02 0.76–1.38 0.8736 0.99 0.73–1.35 0.9738 0.77 0.6–0.98 0.0307 0.75 0.58–0.96 0.0223
Relative weight gain in infancy 1.54 1.14–2.09 0.0050 1.65 1.2–2.26 0.0021 1.21 0.95–1.55 0.1237 1.23 0.96–1.59 0.1046
Relative weight gain in mid-childhood 1.20 0.94–1.54 0.1522 1.28 0.96–1.7 0.0918 1.25 0.99–1.57 0.0653 1.26 0.98–1.62 0.0712
Relative linear growth in infancy 1.76 1.28–2.43 0.0005 1.72 1.26–2.35 0.0007 0.84 0.64–1.11 0.2157 0.84 0.64–1.11 0.2299
Relative linear growth in mid-childhood 1.65 1.24–2.18 0.0005 1.58 1.19–2.11 0.0018 0.85 0.67–1.09 0.2021 0.89 0.7–1.15 0.3774
Upper vs Lower trajectory group
Birth weight(z score) 1.03 0.7–1.51 0.8705 1.02 0.66–1.56 0.9453 0.69 0.31–1.55 0.3652 0.67 0.28–1.61 0.3685
Relative weight gain in infancy 1.58 1.08–2.33 0.0190 1.67 1.09–2.56 0.0196 3.74 1.43–9.83 0.0074 4.11 1.25–13.51 0.0202
Relative weight gain in mid-childhood 1.34 0.95–1.89 0.0950 1.36 0.92–2.02 0.1221 1.21 0.59–2.48 0.6088 1.20 0.54–2.65 0.6604
Relative linear growth in infancy 2.15 1.41–3.28 0.0004 2.18 1.39–3.43 0.0007 1.62 0.67–3.93 0.2847 1.98 0.71–5.48 0.1912
Relative linear growth in mid-childhood 1.44 1–2.09 0.0513 1.53 1.02–2.3 0.0400 1.02 0.44–2.34 0.9645 1.12 0.39–3.2 0.8392
B.GIRLS
Middle vs Lower trajectory group
Birth weight(z score) 1.23 0.93–1.63 0.1490 1.12 0.85–1.48 0.4309 1.09 0.84–1.42 0.5190 0.97 0.73–1.28 0.8223
Relative weight gain in infancy 1.39 1.04–1.86 0.0276 1.37 1.02–1.85 0.0350 1.33 1.02–1.75 0.0378 1.33 1–1.76 0.0492
Relative weight gain in mid-childhood 1.00 0.75–1.32 0.9802 1.09 0.81–1.46 0.5669 1.11 0.85–1.44 0.4507 1.22 0.93–1.59 0.1546
Relative linear growth in infancy 2.11 1.51–2.94 0.0000 2.07 1.48–2.91 0.0000 1.60 1.15–2.21 0.0053 1.58 1.15–2.17 0.0046
Relative linear growth in mid-childhood 1.14 0.87–1.49 0.3394 1.12 0.85–1.48 0.4209 1.03 0.79–1.36 0.8098 1.01 0.75–1.35 0.9578
Upper vs Lower trajectory group
Birth weight(z score) 1.34 0.93–1.94 0.1123 1.31 0.89–1.92 0.1682 1.35 0.94–1.94 0.1043 1.27 0.86–1.88 0.2246
Relative weight gain in infancy 1.67 1.14–2.44 0.0085 1.59 1.06–2.37 0.0236 1.69 1.14–2.5 0.0084 1.63 1.08–2.46 0.0211
Relative weight gain in mid-childhood 1.65 1.18–2.31 0.0038 1.76 1.22–2.55 0.0026 1.69 1.2–2.38 0.0026 1.77 1.22–2.56 0.0025
Relative linear growth in infancy 2.35 1.59–3.48 0.0000 2.23 1.48–3.35 0.0001 1.98 1.33–2.96 0.0008 1.90 1.27–2.86 0.0019
Relative linear growth in mid-childhood 1.95 1.37–2.78 0.0002 1.99 1.36–2.91 0.0004 2.03 1.38–2.99 0.0003 2.12 1.39–3.23 0.0005
*

The multinomial logistic regression showing odds ratios, 95% confidence intervals and the p values from GBTM showing:

Model 1: Multinomial logistic regression of growth variables and SBP trajectory classes adjusted for gestational age (time-invariant covariate-a proxy for intrauterine environment).

Model 2: Multinomial logistic regression of growth variables and SBP trajectory classes adjusted for gestational age, parity, SES in infancy, maternal age (time-invariant covariates-intrauterine environment and maternal factors).

Model 3: Multinomial logistic regression of growth variables and SBP trajectory classes with height as time-varying covariate (a marker of childhood environment) and gestational age as a time-invariant covariate.

Model 4: Multinomial logistic regression of growth variables and SBP trajectory classes with height as time varying covariate and gestational age, parity, SES in infancy, and maternal age as a time-invariant covariates.